Development of an innovative peat lipstick based on the UV-B protective effect of humic substances

Development of an innovative peat lipstick based on the UV-B protective effect of humic substances

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Humic acids (HA) are known for their antiviral and UV-B protecting effects, and are considered promising as ingredients for a UV-protective lipstick which is being developed to minimise or even prevent recurrences of UV- induced herpes.In this study, the UV/Vis spectra of three natural HA and three synthetic HA-like substances are analysed to determine the appropriateness of their UV-absorbing characteristics for the product under development.The contribution of a matrix component (castor oil) to the total UV absorption of the lipstick is also assessed.The results confirm the expected high UV-B absorption Manganese of the individual test substances, but reveal considerable differences S.R. CALME MENTAL in the UV-A wavelength range.

Castor oil absorbs only UV-B radiation; and when mixed with HA it enhances total absorption in the UV-B range, but reduces it in the UV-A range.This is probably due to molecular interactions between castor oil and HA.Preliminary results from cultures of human U937 cells assayed for survival 24 hours after exposure to UV-B radiation show that both HA and castor oil exert a significant concentration-dependent UV-B protective filter effect similar to that of the UV-B absorbing reference substance p-aminobenzoic acid (PABA).